Published Lessons Learned

Occupational HIV Infection in a Research Laboratory With Unknown Mode of Transmission: A Case Report
A. Soria, C. Alteri, G. Scarlatti, A. Bertoli, M. Tolazzi, E. Balestra, M. Concetta Bellocchi, F. Continenza, L. Carioti, M. Biasin, D. Trabattoni, A. Bandera, F. Ceccherini-Silberstein, C. Federico Perno and A. Gori; Clinical infectious disease, 2017, 64(6):810-3.
This report describes a case in which an individual was infected with human immunodeficiency virus (HIV) type 1 during HIV-1 pseudovirus production. Viral genome sequencing and phylogenic analysis suggest that contamination by a replication-competent recombinant clone might have caused the infection. This type of accidents higlights the inherent biohazards in research labs that work with HIV-derived contructs.